Yes, 四神汤 can be made with 薏米 (yìmǐ) and 芡实 (qiànshí) in addition to the traditional ingredients of 白术 (báizhú) and 桂枝 (guìzhī). 薏米 is believed to have a diuretic effect and help with water retention, while 芡实 is believed to tonify the spleen and regulate digestion.
